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Tesamorelin

Also known as: Egrifta, Egrifta SV, Egrifta WR, Tesamorelin acetate, TH9507

Classification

Peptide

Regulatory Status

FDA-approved prescription product

Sources

5

Review

n/a

Overview

Tesamorelin is a synthetic analogue of human GHRH that stimulates pituitary release of endogenous growth hormone and increases IGF-1.

Evidence and limitations

Human/preclinical evidence breakdown is not available in this record.

Pathways

gh-igf1-axisvisceral-adipose-regulationGHRH receptor agonismendogenous GH releaseIGF-1 increaseGHRH receptor

Benefits

FDA-labeled (Egrifta family) for reducing excess abdominal fat in HIV-infected adults with lipodystrophy; not labeled for general weight loss or anti-aging.

Interactions & cautions

exogenous growth hormone or other GH secretagogues — Additive IGF-1 elevation and fluid-retention risk (review)

insulin or antidiabetic medications — Glycemic control may worsen or require regimen changes (review)

These are observational flags for review, not individualized instructions.

Sources

Educational reference only — not medical advice.

What people report (anecdote)

CLINICAL DATA (from trials)

Adverse events:

None recorded in our sources.

Effects measured:

Human trials: none found.

ANECDOTE

What people report: anecdote, not evidence

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Tesamorelin: what the evidence actually says | BioStack