St John's wort
Also known as: Hypericum perforatum
Classification
Supplement
Regulatory Status
n/a
Sources
1
Review
n/a
Overview
St John's wort is a botanical discussed for depressive symptoms and is a known inducer of drug-metabolizing pathways. This record does not establish a treatment plan.
Evidence and limitations
Human/preclinical evidence breakdown is not available in this record.
Pathways
serotonincyp3a4botanical extractdrug-metabolism inductionhyperforin
Benefits
A PubMed systematic review examined St John's wort for major depressive disorder.
Interactions & cautions
Flagged in source data
CYP3A4 and P-glycoprotein substrates
These are observational flags for review, not individualized instructions.
Sources
Educational reference only — not medical advice.
What people report (anecdote)
CLINICAL DATA (from trials)
Adverse events:
None recorded in our sources.
Effects measured:
Human trials: none found.
ANECDOTE
What people report: anecdote, not evidence
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