Survodutide
Also known as: BI 456906, BI-456906
Classification
Peptide
Regulatory Status
Overview
Survodutide (BI 456906) is an investigational dual agonist of the glucagon receptor and GLP-1 receptor studied for obesity and MASH with fibrosis.
Evidence and limitations
Human/preclinical evidence breakdown is not available in this record.
ClassB source cannot establish canonical regulatory or safety fields. The statements below are retained as uncertainty, not as a label-backed verdict. | Regulatory status: not-established | Contraindication: No approved US label; investigational dual agonist is not an authorized consumer product | Warning: Clinical trials report frequent gastrointestinal adverse events and higher discontinuation versus placebo | Adverse effect: nausea | Adverse effect: diarrhea | Adverse effect: vomiting | Adverse effect: other gastrointestinal events in trials | Serious adverse effect: full serious-risk profile not established in an approved US label; treatment discontinuations due to adverse events were substantially higher than placebo in trials
Pathways
Interactions & cautions
Drug interactions
other GLP-1 or dual/triple incretin agonists — Additive GI and metabolic effects may occur. (review)
These are observational flags for review, not individualized instructions.
Sources
Educational reference only — not medical advice.