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Milk thistle

Also known as: Silybum marianum, silymarin

Classification

Supplement

Regulatory Status

Overview

Silymarin is a flavonolignan mixture from milk thistle discussed in liver contexts. A hepatoprotective effect is not established as a recommendation.

Evidence and limitations

Human/preclinical evidence breakdown is not available in this record.

ClassB source cannot establish canonical regulatory or safety fields. The statements below are retained as uncertainty, not as a label-backed verdict. | Regulatory status: not-established | Warning: Allergic reactions and a laxative effect are discussed | Precaution: Risk profile is not a personal clearance | Adverse effect: gastrointestinal upset | Serious adverse effect: allergic reaction

Pathways

hepatic-discussionflavonolignan extractsilymarin

Benefits

A PubMed systematic review and meta-analysis examined silymarin administration in NAFLD/NASH.

Interactions & cautions

drugs metabolized by CYP enzymes

These are observational flags for review, not individualized instructions.

Sources

Educational reference only — not medical advice.

Milk thistle Research & Evidence | BioStack