Gonadorelin
Also known as: GnRH, Factrel, LHRH, Gonadorelin acetate, Gonadorelin hydrochloride, Lutrepulse
Classification
Hormone
Regulatory Status
not-established
Overview
Gonadorelin is the synthetic form of native hypothalamic gonadotropin-releasing hormone (GnRH/LHRH), a decapeptide that acts on the anterior pituitary to stimulate release of luteinizing hormone (LH) and follicle-stimulating hormone (FSH).
Evidence and limitations
Human/preclinical evidence breakdown is not available in this record.
Pathways
Gonadorelin is the synthetic form of native hypothalamic gonadotropin-releasing hormone (GnRH/LHRH), a decapeptide that acts on the anterior pituitary to stimulate release of luteinizing hormone (LH) and follicle-stimulating hormone (FSH).
Interactions & cautions
Drug interactions
other gonadotropin or GnRH therapies — Unpredictable LH/FSH responses and reproductive hormone swings (review)
These are observational flags for review, not individualized instructions.
Sources
- https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=1451663c-b85a-4b45-8b27-6d572d0032f9 (opens in a new tab)
- https://ferring.ca/media/1018/lutrepulse-pm-control-no-187199-32-mg-en_17may2016.pdf (opens in a new tab)
- https://www.mayoclinic.org/drugs-supplements/gonadorelin-intravenous-route-injection-route/description/drg-20067426 (opens in a new tab)
Educational reference only — not medical advice.